DIFFERENTIAL RESPONSE TO MUTAGENS AS STUDIED BY THE NEUROSPORA REVERSE MUTATION TEST

Superoxide dismutase (sod-1) null mutants of Neurospora crassa: oxidative stress sensitivity, spontaneous mutation rate and response to mutagens.

Enzymatic superoxide-dismutase activity is believed to be important in defense against the toxic effects of superoxide. Although superoxide dismutases are among the best studied proteins, numerous questions remain concerning the specific biological roles of the various superoxide-dismutase types. In part, this is because the proposed damaging effects of superoxide are manifold, ranging from ina...

the differential effects of debate and media analysis as relate to enhancing efl learners critical thinking ability and writing performances

critical thinking ability has an important role in education. accordingly, scholars around the world are searching for new ways for teaching and improving students critical thinking ability. in line with the studies in efl contexts supporting the positive relationship between critical thinking and writing performances, this study investigated the differential effects of halverson’s critical thi...

Differential Gene Response to Mutagens in Drosophila Melanogaster.

Mutation and Mutagens Definitions

somatic mutation: a mutation in a somatic cell; somatic mutations produce "mosaic" or "chimeric' organisms since they have sectors of cells with different genotypes. In some plants and fungi tissue from the "mutant" sector may be grown into a whole reproducing organism; some of our better apple varieties arose from mutant sectors on a tree. Somatic mutations in animals can lead to cancer when g...

Mutagenicity of flavonoids assayed by bacterial reverse mutation (Ames) test.

The mutagenicity of ten flavonoids was assayed by the Ames test, in Salmonella typhimurium strains TA98, TA100 and TA102, with the aim of establishing hydroxylation pattern-mutagenicity relationship profiles. The compounds assessed were: quercetin, kaempferol, luteolin, fisetin, chrysin, galangin, flavone, 3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone. In the Ames assay, quer...